PRX Biorevitalization (Derm Perfexion, PRX-PLUS, PRX C)

Medically reviewed by Deborah Lenchus, MSN, APRN · Last reviewed August 2026

What is PRX?

PRX is a professional, in-office topical treatment applied to the skin by massage — no needles, no injections and no laser energy. It is often described as “biorevitalization” rather than a peel, because it is designed to stimulate the deeper layer of the skin while leaving the surface intact. LuXe Concierge Aesthetics is an authorized PRX provider, and every treatment is performed personally by nurse practitioner Deborah Lenchus, MSN, APRN.

How PRX works

The original formula, PRX Derm Perfexion, combines 33% trichloroacetic acid (TCA), hydrogen peroxide and 5% kojic acid. On its own, TCA at that concentration would coagulate the surface of the skin and cause frosting and visible peeling. The hydrogen peroxide modulates that effect, so the formulation can stimulate the dermis — where collagen is made — without stripping the epidermis. Kojic acid contributes to a more even-looking tone.

Because the surface layer is preserved, PRX behaves very differently from a resurfacing peel or laser: there is no wound to heal, and therefore very little downtime. What it shares with those treatments is the goal — prompting the skin to build new collagen over the weeks that follow. Improvement is gradual, and individual results vary.

The three PRX formulas we carry

PRX Derm Perfexion

The original and most versatile formula. Used for overall rejuvenation, fine lines, rough or crepey texture, mild laxity, dullness, and the appearance of acne scarring and stretch marks. It can be used on the face, neck, décolletage, hands and body.

PRX-PLUS

A more advanced formulation built around a modified acid system with homocysteic acid. It is aimed at more stubborn concerns — uneven pigmentation, deeper lines and loss of firmness — in patients who want a stronger correction than the original formula provides.

PRX C

Focused on radiance and antioxidant support. A good fit for skin that reads as tired, devitalized or dull, and often used to add luminosity alongside the other formulas.

What PRX is used for

  • Fine lines and early skin laxity
  • Rough, crepey or uneven texture
  • Dull, tired-looking skin
  • Uneven tone and selected pigment concerns, when clinically appropriate
  • The appearance of acne scarring
  • The appearance of stretch marks
  • Neck, décolletage and hands, not just the face

What to expect

Treatment takes roughly 15 to 30 minutes. After cleansing, the solution is massaged into the skin in layers, then rinsed, and a post-treatment cream is applied. Most people feel mild warmth or tingling. A typical starting course is four sessions about a week apart, with maintenance afterward; concerns like scarring generally need the fuller series. You will leave with home-care instructions, and daily sunscreen is part of the plan.

How PRX fits with your other treatments

PRX is frequently combined with other collagen-building work rather than used alone. It pairs naturally with DP4 microneedling and RF microneedling, with Density RF skin tightening, and with injectable biostimulators such as Sculptra and Radiesse. Because it does not resurface the skin, it is also a practical option between chemical peels or laser resurfacing sessions, and for patients who cannot take downtime. For a fuller picture of how these layer together, see our guide to rebuilding and protecting collagen.

Who is not a candidate

PRX is not appropriate during pregnancy or breastfeeding, for anyone with a known kojic acid allergy, or over skin that is actively irritated, infected, sunburned, or affected by conditions such as seborrheic dermatitis. Recent isotretinoin use, a history of keloid scarring and current skincare actives all need to be reviewed first. Deborah takes a full health history at consultation and will tell you honestly if PRX is not the right treatment for your skin.

Book a PRX consultation in Davie

PRX is available at LuXe Concierge Aesthetics in Davie, serving Weston, Cooper City, Plantation, Southwest Ranches, Sunrise and Fort Lauderdale. Current pricing for single treatments and packages is shown when you book online, or call (754) 715-5667.

Frequently Asked Questions

Is PRX a chemical peel?

No. Although PRX Derm Perfexion contains trichloroacetic acid (TCA), which has historically been used as a peeling agent, the formulation also contains hydrogen peroxide, which buffers the TCA so it does not coagulate the surface of the skin. The result is stimulation in the deeper layer without the visible peeling associated with a conventional chemical peel. It is applied topically by massage — there are no needles and no injections.

Is there downtime after PRX?

Most people return to normal activities the same day. Mild redness, tightness or light flaking for a day or two is possible. Your provider will review what to expect for your skin and your treatment plan.

How many PRX treatments will I need?

A typical starting course is four treatments spaced about one week apart, with maintenance sessions afterward. The right number depends on what is being treated — textural concerns and scarring generally need a fuller series. Individual results vary and your plan is set at consultation.

What is the difference between PRX Derm Perfexion, PRX-PLUS and PRX C?

PRX Derm Perfexion is the original formula (TCA, hydrogen peroxide and kojic acid) used for overall rejuvenation, texture and firmness. PRX-PLUS uses a modified acid system with homocysteic acid and is aimed at more advanced concerns such as stubborn pigmentation and loss of firmness. PRX C is focused on radiance and antioxidant support for dull, tired-looking skin. Deborah selects the formula, or the combination, at consultation.

Who should not have PRX?

PRX is not appropriate during pregnancy or breastfeeding, with a known kojic acid allergy, or over skin that is actively irritated, infected, sunburned or affected by conditions such as seborrheic dermatitis. Recent isotretinoin use also needs to be discussed. A full health history is reviewed before treatment.

Can PRX be done in the summer?

PRX does not cause the photosensitization associated with some resurfacing treatments, so it is commonly performed year-round. Daily broad-spectrum sunscreen is still required, both to protect results and to protect your skin.

Individual results vary. This page is educational and is not a substitute for a medical consultation. PRX®, PRX Derm Perfexion®, PRX-PLUS® and PRX C® are trademarks of WiQo®.

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